Tuesday, April 2, 2013

Principles and Methods of Toxicology, Fifth Edition



Principles and Methods of Toxicology, Fifth Edition by A. Wallace Hayes (Editor). Based on the paradox that all things are poisons and the difference between poison and treatment is amount, the dedication of safe dosage types the base and focus of contemporary toxicology. In an effort to make a sound dedication there must be a working information of the biologic mechanisms involved and of the strategies employed to define these mechanisms. Whereas the vastness of the field and the fast accumulation of information might preclude the opportunity of absorbing and retaining more than a fraction of the obtainable info, a solid understanding of the underlying ideas is essential.

Extensively revised and updated with four new chapters and an expanded glossary, this fifth version of the basic textual content, Principles and Strategies of Toxicology offers comprehensive protection in a manageable and accessible format. New subjects include ‘toxicopanomics’, plant and animal poisons, data assets, and non-animal testing alternatives. Emphasizing the cornerstones of toxicology-people differ, dose issues, and things change, the guide begins with a review of the historical past of toxicology and adopted by an explanation of primary toxicological rules, agents that trigger toxicity, goal organ toxicity, and toxicological testing strategies including lots of the test protocols required to meet regulatory wants worldwide. The guide examines every technique or process from the standpoint of technique and interpretation of information and discusses issues and pitfalls that could be related to each. The addition of several new authors allow for a broader and more diverse therapy of the ever-changing and expanding discipline of toxicology.

Sustaining the high-high quality information and organizational framework that made the earlier editions so successful, Rules and Methods of Toxicology, Fifth Edition continues to be a valuable resource for the superior practitioner as well as the brand new disciple of toxicology.


This guide is every little thing I ever needed in a toxicology text and by no means had at school, because “the other” toxicology guide was prescribed. Principles and Methods is near-seamlessly edited, rationally content material-structured, and authored by experts with innate gifts of written communication. The Hayes textual content is such a breath of contemporary air after using the opposite one for therefore many years that had substantial content material overlap in numerous chapters, “holes” of content protection that would seem clearly inside the scope, and a too-skinny index. I strongly suggest this textual content to graduate students in toxicology, skilled toxicologists, and our companions in pathology.

I’m a graduate pupil working on a PhD, and my emphasis is in tox/medical sciences. This guide is a superb reference for anyone who needs to exand their information in tox principle and methodology! It’s on my high shelf, proper beside Casarett and Doulls. The organizational strategy to this e-book is great, and pertinent examples are given in every section. Applause, applause.

If you want to enjoy studying toxicology, learn Hayes. This guide is so a lot better written than C&D. If finding out for ABT, this is a nice supplement.

Principles and Methods of Toxicology, Fifth Edition
A. Wallace Hayes (Editor)
2296 pages
CRC Press; 5 edition (September 25, 2007)

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